Read articles related to the project

post image

Satellite‐congress EAS 2019

Over 50 participants attended the inspiring satellite-congress EAS 2019, co-organized by REPROGRAM, focused on the “Interplay of metabolism, inflammation and vascular biology”. On behalf of REPROGRAM Prof. Niels Riksen (Radboud UMC), Prof. Erik Stroes (Academic Medical Center) and Prof. Matthias Nahrendorf (Harvard Medical School) presented their work and emerging results. This symposium was open to

Read More →

post image

Joint session (open-end conference) of the REPROGRAM project at the EAS SATELLITE on IMMUNOMETABOLISM (26 May 2019)

Read More →

Open-end congres REPROGRAM at EAS

On May 26 until May 29 2019 the open-end congres of REPROGRAM will be held at the 87th European Atherosclerosis Society in Maastricht. You can sign in with the following link: https://eas2019.com/the-congress/satellite-symposia/immunometabolism/ Untitled

Read More →

post image

Grant application MEMORY funded by European Research Area Network on Cardiovascular Diseases (ERA-CVD)

Prof. Niels RIksen (RadboudUmc, Nijmegen) teamed up with dr. Andreas Schlitzer (University of Bonn, Germany)  and dr. Hafid Ait-Oufella (St-Antoine Hospital and Inserm , France). They prepared a successful  transnational ERA-CVD research application entitled MEMORY. Due to the worldwide adoption of Western lifestyle, the prevalence of obesity increases exponentially. Obesity is an important risk factor for

Read More →

Governing Council meeting 2019

On January 21 2019, the Governing Council meeting was held at Schiphol Amsterdam airport for the REPROGRAM project. After a warm welcome by Prof. Dr. Erik Stroes (Project Coordinator) the meeting started immediately with presentations of Prof. dr. Niels Riksen (RadboudUMC), Prof. dr. Erik Stroes (AMC), Prof dr.Borge Nordestgaard (Copenhagen University Hospital) and Prof. dr.

Read More →

post image

Review article in Atherosclerosis: “Potential epigenetic therapeutics for atherosclerosis treatment”

The AMC groups of Prof. Stroes and Prof. de Winther published recently a review article on epigenetic therapeutics for atherosclerosis in the Atherosclerosis journal. Common epigenetic modifications such as DNA methylation and histone post-translational modifications are in the spotlight of epigenetic therapeutics and are show promise for the treatment of many diseases including cancer, diabetes,

Read More →

post image

Analyses in the primary prevention setting substantiate that LDL-C and Lp(a) are independently associated with CVD risk.

Lipoprotein(a) (Lp(a)) elevation is a causal risk factor for cardiovascular disease. It has however been suggested that elevated Lp(a) causes cardiovascular disease mainly in individuals with high low-density lipoprotein cholesterol (LDL-C) levels. Therefore it was hypothesized that the risk associated with high Lp(a) levels would largely be attenuated at low LDL-C levels. Results from the Copenhagen City Heart

Read More →

post image

Review article on potential epigenetic compounds that could be utilized to prevent or treat atherosclerosis.

In a collaborative effort between the groups of Vascular Medicine and Medical Biochemistry of the Academic Medical Center (Prof. Erik Stroes, Prof. de Winther) a review article has been published in the esteemed Athersclerosis journal (Oct, 2018). In this review, potential epigenetic compounds are studied that could be utilized to prevent or treat atherosclerosis based on

Read More →

post image

Promising imaging results published on multi-level inflammatory responses in acute coronary syndrome.

In the first 6–9 months following an acute coronary syndrome (ACS), patients face a disproportionally increased risk of reinfarction. Following an ACS in patients, studies have substantiated that 18F-fluordeoxyglucose (18F-FDG) uptake in bone-marrow and spleen is increased, visualized with positron emission tomography/ computed tomography (PET/CT). This increased uptake coincides with increased inflammatory parameters in plasma

Read More →

post image

Review: The maturation of a key inflammatory axis in cardiovascular disease

The groups of Prof. Stroes (Amsterdam) and Prof. Nahrendorf (Boston) reviewed recent advances in the connection between hematopoiesis and atherogenesis. Atherogenesis is the result of a complex interplay between lipids and innate immune cells, which are descendants of upstream progenitors residing in hematopoietic organs. The relevance of a neural–hematopoietic axis was recently supported by the demonstration of

Read More →

1 2 3 4 6

This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement N°667837.